| INRAE, UMR 1313 Génétique Animale et Biologie Intégrative
Domaine de Vilvert, Bat 211, 78352 Jouy en Josas
Tel : +33 (0) 1 34 65 21 81
orcid.org/0000-0003-0361-2961 Email : didier.boichard(at)inrae.fr |
Équipe Génétique et Génomique Bovine
CV :
- Ingénieur agronome de l’Institut National Agronomique Paris Grignon, 1982
- DEA de Génétique quantitative, Paris VI, 1985
- Thèse de docteur ingénieur de l’INA Paris Grignon, 1987
- Chargé de recherche INRAE (1987) puis Directeur de Recherche (1996)
- Directeur du Département de Génétique Animale de 2002 à 2009
- Président du GIE Labogena de 2004 à 2013
- Membre de l'Académie Vétérinaire de France
- Médaille d'Or de l'Académie d'Agriculture de France (2015)
- L'équipe G2B a reçu le Laurier de l'Impact de INRAE en 2016, pour son activité de sélection génomique bovine
Domaines de recherche :
Sélection génomique ; amélioration génétique des bovins ; génétique quantitative ; évaluation génétique des reproducteurs ; cartographie de QTL ; déterminisme génétique de la composition du lait ; déterminisme génétique de la fertilité ; déterminisme génétique de la résistance aux mammites ; gènes à effets majeurs et anomalies génétiques.
Autres activités :
Sélection de Publications :
Jourdain J., Barasc H., Faraut T., Calgaro A., Bonnet N., Marcuzzo C., Suin A., Barbat A., Hoze C., Besnard F., Taussat S., Grohs C., Kuchly C., Iampietro C., Donnadieu C., Pinton A., Boichard D., Capitan A. 2023. Large-scale detection and characterization of interchromosomal rearrangements in normozoospermic bulls using massive genotype and phenotype datasets. Genome Research, 33: 957-971.
Sahana G, Cai Z., Sanchez M.P., Bouwman A., Boichard D. 2023. Invited review: Good practices in genome-wide association studies to identify candidate sequence variants in dairy cattle. J Dairy Sci, 106, 5218–5241.
Sanchez M.P., Escouflaire C., Baur A., Bottin F., Hoze C., Boussaha M., Capitan A., Fritz S., Capitan A., Boichard D. 2023. X-linked genes influence various complex traits in dairy cattle. BMC Genomics, 24:338.
Smith T.P.L., Bickhart D.M., Boichard D., Chamberlain A.J., Djikeng A., Jiang Y., Low W.Y., Pausch H., Demyda-Peyrás S., Prendergast J., Schnabel R.D., The Bovine Pangenome Consortium, Rosen B.D. 2023. The Bovine Pangenome Consortium: democratizing production and accessibility of genome assemblies for global cattle breeds and other bovine species. Genome Biology, 24, 139.
Tribout T., Minéry S., Vallée R., Saille S., Saunier D., Martin P., Ducrocq V., Faverdin P., Boichard D. 2023. Genetic relationships between weight loss in early lactation and daily milk production throughout the lactation in Holstein cows. J Dairy Sci, 106, 4799–4812.
Fresco S., Boichard D., Fritz S., Lefebvre R., Barbey S., Gaborit M., Martin P. 2023. Comparison of methane production, intensity, and yield throughout lactation in Holstein cows. J Dairy Sci, 106, 4147–4157.
Vinet A., Mattalia S., Vallée R., Bertrand C., Cuyabano B.C.D., Boichard D. 2023. Estimation of genotype by temperature-humidity index interactions on milk production and udder health traits in the Montbeliarde cows. Genet Sel Evol, 55, 4.
Eche C., Iampietro C., Birbes C., Dreau A., Kuchly C., Di Franco A., Klopp C., Faraut T., Djebali S., Castinel A., Zytnicki M., Denis E., Boussaha M., Grohs C., Boichard D., Gaspin C., Milan D., Donnadieu C., 2023. A Bos taurus sequencing methods benchmark for assembly, haplotyping, and variant calling. Scientific Data, 10:369.
Boussaha M., Boulling A., Wolgust V., Bourgeois-Brunel L., Michot P., Grohs C., Gaiani N., Grivaud P.Y., Leclerc H., Danchin-Burge C., Vilotte M., Boichard D., Gourreau J.M., Capitan A. 2023. Integrin alpha-6 homozygous splice-site mutation causes a new form of junctional epidermolysis bullosa in Charolais Cattle. Genet Sel Evol, 55, 40.
Lefebvre R., Faverdin P., Barbey S., Jurquet J., Tribout T., Boichard D., Martin P. 2023. Association between body condition genomic values and feed intake, milk production, and body weight in French Holstein cows. J Dairy Sci, 106, 381-391.
Besnard F., Boussaha M., Leclerc H., Grohs C., Jewell N. Pinton A. Barsac H., Jourdain J., Femenia M., Dorso L., Strugnell B., Floyd T., Danchin-Burge C., Guatteo R., Cassart D., Hubin X., Mattalia S., Boichard D., Capitan A. 2023. Detailed analysis of mortality rates in the female progeny of 1001 Holstein bulls allows the discovery of new dominant genetic defects. J Dairy Sci, 106, 439-451.
Sanchez M.P., Tribout T., Fritz S., Guatteo R., Fourichon C., Schibler L., Delafosse A., Boichard D. 2022. New insights into genetic resistance to paratuberculosis in Holstein cattle via a single-step genomic evaluation. Genet Sel Evol, 54: 67.
Vaiman A., Fritz S., Beauvallet C., Boussaha M., Grohs C., Daniel-Carlier N., Relun A., Boichard D., Vilotte J.L., Duchesne A. Mutation of MYH3 gene causes recessive cleft palate syndrome in Limousin cattle. Genet Sel Evol. 54:71.
Sanchez M.P., Tribout T., Fritz S., Wolf V., Laithier C., Brochard M., Boichard D. 2022. Opportunities for genomic selection of cheese-making traits in Montbéliarde cows. J Dairy Sci, 105, 5206-5220.
Lesueur J., Walachowski S., Barbey S., Cebron N., Lefebvre R., Launay F., Boichard D., Germon P., Corbiere F., Foucras G. 2022. Standardized whole blood assay and bead-based cytokine profiling reveal commonalities and diversity of the response to bacteria and TLR ligands in cattle. Front. Immunol., 13:871780.
Costes V., Chaulot-Talmon A., Sellem E., Perrier J.P., Aubert-Frambourg A., Jouneau L., Pontlevoy C., Hozé C., Fritz S., Boussaha M., Le Danvic C., Sanchez M.P., Boichard D., Schibler L., Jammes H., Jaffrézic F., Kiefer H. 2022. Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records. Clinical Epigenetics 14, 54
Mesbah-Uddin M., Guldbrandtsen B., Capitan A., Lund M.S., Boichard D., Sahana G. 2022. Genome-wide association study with imputed whole-genome sequence variants including large deletions for female fertility in 3 Nordic dairy cattle breeds. J. Dairy Sci, 105, 1298–1313.
Sanchez M.P., Rocha D., Charles M., Boussaha M., Hozé C., Brochard M., Delacroix-Buchet A., Grosperrin P., Boichard D. 2021. Sequence-based GWAS and post-GWAS analyses reveal a key role of SLC37A1 and ANKH genes and gene regulatory regions on bovine milk minerals. Scientific Reports, 11, 7537.
Rostellato R., Promp J., Leclerc H., Mattalia S., Friggens N.C., Boichard D., Ducrocq V. Influence of production, reproduction, morphology and health traits on true and functional longevity in French Holstein cows. J Dairy Sci, 104, 12664–12678.
Bourdon C, Boussaha M, Bardou P, Sanchez MP, Le Guillou S, Tribout T, Larroque H, Boichard D, Rupp R, Le Provost F, Tosser-Klopp G. 2021. In silico whole genome SNP datasets analyses identify variations in microRNAs with a potential impact on dairy traits in bovine, caprine and ovine species. Scientific Reports 11, 19580.
Floriot S., Duchesne D., Grohs C., Hozé C., Deloche M.C., Fayolle G., Vilotte J.L., Boichard D., Fritz S., Boussaha M. 2021. A missense mutation in the FZD7 gene is associated with dilution of the red areas of the coat in Montbéliarde cattle. Animal Genetics, 52, 351-355.
Lefebvre R., Larroque H., Barbey S., Gallard Y., Colleau J.J., Lainé A.L., Boichard D., Martin P. 2021. Genome wide association study for age at puberty and resumption of cyclicity in a French crossbred cattle population. J. Dairy Sci. 104, 5794-5804.
Bérodier M., Berg P., Meuwissen T.H.E., Boichard D., Brochard M., Ducrocq V. 2021. Improved dairy cattle mating plans at herd level using genomic information. Animal, 15:100016.
Ben Abdelkrim A., Tribout T., Martin O., Boichard D., Ducrocq V., Friggens N.C. 2021. Exploring simultaneous perturbation profiles in milk yield and body weight reveals a diversity of animal responses and new opportunities to identify resilience proxies. J Dairy Sci. 104: 459-470.
Zhang J., Kadri N., Mullaart E., Spelman R., Fritz S., Boichard D., Charlier C., Georges M., Druet T. 2020. Genetic architecture of individual variation in recombination rate on the X-chromosome in cattle, Heredity, 125:304–316.
Tribout T., Croiseau P., Lefebvre R., Barbat A., Boussaha M., Fritz S., Boichard D., Hoze C., Sanchez M.P. 2020. Confirmed candidate causative variants for milk production, udder health and udder morphology in dairy cattle. Genet Sel Evol, 52: 55.
Boichard D. 2020. Nouvelles modalités de diffusion de la génétique. In “Génétique des animaux d'élevage : Diversité et adaptation dans un monde changeant”, Quae, E Verrier, D Milan, C Rogel-Gaillard Eds, chapitre 12, 193-203.
Sanchez M.P., Fritz S., Patry C., Delacroix-Buchet A., Boichard D. 2020. Milk protein variant and haplotype frequencies estimated from genotypes of more than one million bulls and cows of twelve French cattle breeds. J Dairy Sci, 103: 9124-9141.
Sanchez M.P., Guatteo R., Davergne A., Saout J., Grohs C., Deloche M.C., Taussat S., Fritz S., Boussaha M., Blanquefort P., Delafosse A., Joly A., Schibler L., Fourichon C., Boichard D. 2020. Identification of the ABCC4, IER3 and CBFA2T2 candidate genes for resistance to paratuberculosis in Holstein and Normande dairy cattle from a sequence-based GWAS. Genet Sel Evol, 52: 14.
Van Den Berg I., Xiang R., Jenko J., Pausch H., Boussaha M., Tribout T., Gjuvsland A.B., Boichard D., Nordbø Ø., Sanchez M-P., Goddard M.E. 2020. Large scale multi breed meta-analysis for fat and protein percentage using imputed sequence variant genotypes in 94,321 cattle from eight dairy breeds. Genet Sel Evol, 52: 37.
Liu A., Lund M.S., Boichard D., Karaman E., Guldbrandtsen B., Fritz S., Aamand G.P., Nielsen U.S., Sahana G., Wang Y., Su G. 2020. Weighted single-step genomic best linear unbiased prediction integrating the variants selected from sequencing data by association and bioinformatics analyses. Genet Sel Evol, 52: 48.
Liu A., Lund M.S., Boichard D., Mao X., Karaman E., Fritz S., Pedersen Aamand G., Wang Y., Su G. 2020. Imputation for sequencing variants preselected to a customized low-density chip. Sci Rep, 10: 9524.
Hozé C., Escouflaire C., Mesbah-Uddin M., Barbat A., Boussaha M., Deloche M.C., Boichard D., Fritz S., Capitan A. 2020. Short Communication: A splice site mutation in CENPU is associated with recessive embryonic lethality in Holstein cattle. J Dairy Sci, 103: 607–612.
Liu A., Lund M.S., Boichard D., Karaman E., Fritz S., Aamand G.P., Nielsen U.S., Wang Y., Su G. 2020. Improvement of genomic prediction by additional single nucleotide polymorphisms selected from whole genome sequencing data. Heredity, 124: 37-49.
Boichard D. 2019. Development of dairy breeding programs. Book “Advances of breeding in dairy cattle”, Burleigh-Dodds, Chapitre 23, 16p.
Sanchez M.P., Wolf V., Laithier C., El Jabri M., Beuvier E., Rolet-Repecaud O., Gaudilliere N., Minery S., Ramayo-Caldas Y., Tribout T., Michenet A., Boussaha M., Taussat S., Fritz S., Delacroix-Buchet A., Grosperrin P., Brochard M., Boichard D. 2019. Analyse génétique de la fromageabilité du lait de vache prédite par spectrométrie moyen infrarouge en race Montbéliarde. INRA Productions Animales, 32: 379-398.
Dezetter C., Boichard D., Bareille N., Grimard B., Le Mezec P., Ducrocq V. 2019. Le croisement entre races bovines laitières : Quel intérêt pour des ateliers en race pure Prim’Holstein ? INRA Productions Animales, 32: 359-378.
Sanchez M.P., Ramayo-Caldas Y., Wolf V., Laithier C., El Jabri M., Michenet A., Boussaha M., Taussat S., Fritz S., Delacroix-Buchet A., Brochard M., Boichard D. 2019. Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese making properties and milk composition in Montbéliarde cows. Genet Sel Evol, 51: 34.
El Jabri M., Sanchez M.P., Trossat P., Laithier C., Wolf V., Grosperrin P., Beuvier E., Rolet-Répécaud O., Gavoye S., Gauzere Y., Belysheva O., Notz E., Boichard D., Delacroix-Buchet A. 2019. Comparison of Bayesian and PLS regression methods for mid-infrared prediction of cheese-making properties in Montbéliarde cows. J Dairy Sci, 102: 6943–6958.
Uddin M.M., Hoze C., Michot P., Barbat A., Lefebvre R., Boussaha M., Sahana G., Fritz S., Boichard D., Capitan A. 2019. A missense mutation (p.Tyr452Cys) on CAD gene compromises reproductive success in dairy cattle. J Dairy Sci, 102: 6340–6356.
Mesbah-Uddin M, Guldbrandtsen B, Lund MS, Boichard D, Sahana G. 2019. Joint imputation of whole-genome sequence variants and large chromosomal deletions in cattle. J Dairy Sci, 102: 11193-11206
Navarro-Gonzalez N, Fourichon C, Blanquefort P, Delafosse A, Joly A, Ngwa-Mbot D, Biet F, Boichard D, Schibler L, Journaux L, Meens E, Guatteo R. 2019. Longitudinal Study of Mycobacterium avium subsp paratuberculosis Shedding Patterns and Concurrent Serological Patterns in Naturally Infected Dairy Cattle. J Dairy Sci, 102: 9117-9137.
Bérodier M., Brochard M., Boichard D., Dezetter C., Bareille N., Ducrocq V. 2019. Use of sexed semen and female genotyping impacts genetic and economic outcomes of Montbéliarde dairy herds depending on the farming system considered. J Dairy Sci, 102: 10073–10087.
Sellier P, Boichard D, Verrier E. 2019. La génétique animale à l‘Inra : soixante ans d'une histoire scientifique en prise avec le monde de la sélection et riche en rebondissements technologiques. Histoire Recherche Contemporaine, 8: 86-98.
Boichard D, Mattalia S, Fritz S. 2018. La sélection dans l’espèce bovine et ses perspectives. Bull Acad Vet, 170: 215-220.
Sanchez M.P., El Jabri M., Minery S., Wolf V., Beuvier E., Laithier C., Delacroix-Buchet A., Brochard M., Boichard D. 2018. Genetic parameters for cheese-making properties and milk composition predicted from mid-infrared spectra in a large dataset of Montbéliarde cows. J Dairy Sci, 101: 10048–10061.
Sanchez M.P., Wolf V., El Jabri M., Beuvier E., Rolet-Repecaud O., Gauzere Y., Minery S., Brochard M., Michenet A., Taussat S., Barbat-Leterrier A., Delacroix-Buchet A., Laithier C., Fritz S., Boichard D. 2018. Short-communication: Confirmation of candidate causative variants on milk composition and cheese-making properties in Montbéliarde cows. J Dairy Sci, 101: 10076–10081.
Marete A., Guldbrandtsen B., Lund M.S., Sahana G., Boichard D. 2018. A meta-analysis including pre-selected sequence variants associated with seven traits in three French dairy cattle populations. Frontiers in Genetics, 9: 522.
Duchesne A., Vaiman A., Frah M., Floriot S., Rodriguez S., Desmazieres A., Fritz S., Beauvallet C., Albaric O., Venot E., Bertaud M., Guatteo R., Esquerre D., Brice A., Vilotte J.L., Darios F., Stevanin G., Boichard D., El Hachimi K.H. 2018. Progressive ataxia of Charolais cattle highlights a role of KIF1C in sustainable myelination. Plos Genetics, 14: e1007550.
Rainard P., Foucras G., Boichard D., Rupp R. 2018. Invited review: Low milk somatic cell count and susceptibility to mastitis. J Dairy Sci, 101: 6703-6714.
Rainard P., Foucras G., Boichard D., Rupp R. 2018. Faibles concentrations cellulaires du lait et sensibilité aux mammites des ruminants laitiers. INRA Prod Anim, 31: 365-376.
Perrier J.P., Sellem E., Prezelin A., Gasselin M., Jouneau L., Piumi F., Al Adhami H., Weber M., Fritz S., Boichard D., Le Danvic C., Schibler L., Jammes H., Kiefer H. 2017. A multi-scale analysis of bull sperm methylome revealed both species peculiarities and conserved tissue-specific features. BMC Genomics, 19: 404.
Fritz S., Hoze C., Rebours E., Barbat A., Bizard M., Chamberlain A., Escouflaire C., Vander Jagt C., Boussaha M., Grohs C., Allais-Bonnet A., Philippe M., Vallee A., Amigues Y., Hayes B.J., Boichard D., Capitan A. 2018. An initiator codon mutation in SDE2 causes recessive embryonic lethality in Holstein cattle. J Dairy Sci, 101: 6220-6231.
Marete A.G., Boichard D., Lund M.S., Ramayo-Caldas Y. 2018. A system-based analysis of the genetic determinism of udder conformation and health traits across three French Dairy Breeds. Plos One, 13: e0199931.
Marete A.G., Sahana G., Fritz S., Lefebvre R., Barbat-Leterrier A., Lund M.S., Guldbrandtsen B., Boichard D. 2018. Genome-wide association study for milking speed in French Holstein cows. J Dairy Sci., 101: 6205-6219.
Bouwman A.C., Daetwyler H.D., Chamberlain A.J., Hurtado Ponce C., Sargolzaei M., Schenkel F.S., Sahana G., Govignon-Gion A., Boitard S., Dolezal M., Pausch H., Brøndum R.F., Bowman P.J., Thomsen B., Guldbrandtsen B., Lund M.S., Servin B., Garrick D.J., Reecy J., Vilkki J., Bagnato A., Wang M., Hoff J.L., Schnabel R.D., Taylor J.F., Vinkhuyzen A.A.E., Panitz F., Bendixen C., Holm L.E., Gredler B., Hozé C., Boussaha M., Sanchez M.P., Rocha D., Capitan A., Tribout T., Barbat A., Croiseau P., Drögemüller C., Jagannathan V., Vander Jagt C., Crowley J.J., Intergenomics Consortium, Bieber A., Purfield D.C., Berry D.P., Emmerling R., Götz K.U., Van Tassell C.P, Fries R., Stothard P., Veerkamp R.F., Boichard D., Goddard M.E., Hayes B.J. 2018. Meta-analysis of genome wide association studies for the stature of cattle reveals common genes that regulate size in mammals. Nature Genetics, 50: 362-367, DOI:10.1038/s41588-018-0056-5.
Charton C., Guinard-Flament J, Lefebvre R, Barbey S., Gallard Y, Boichard D, Larroque H. 2017. Genetic determinism of milk production traits in response to a three-week once-daily milking period in crossbred Holstein × Normande dairy cows. J Dairy Sci, 101: 2235–2247.
Mesbah-Uddin M., Guldbrandtsen B., Iso-Touru T., Vilkki J., De Koning D.J., Boichard D., Lund M.S., Sahana G. 2018. Genome-wide mapping of large deletions and their population-genetic properties in dairy cattle. DNA Research, 25: 49-59.
Sanchez M.P., Govignon-Gion A., Croiseau P., Fritz S., Hoze C., Miranda G., Martin P., Barbat-Leterrier A., Brochard M., Boussaha M., Boichard D. 2017. Within-breed and multi-breed GWAS on imputed whole genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle. Genetics Selection Evolution, 49: 68.
Bourneuf E., Otz P., Pausch H., Jagannathan V., Michot P., Grohs C., Piton G., Ammermüller S., Deloche M.C., Fritz S., Leclerc H., Péchoux C., Boukadiri A., Saintilan R., Créchet F., Mosca M., Segelke D., Guillaume F., Bouet S., Baur A., Vasilescu A., Genestout L., Thomas A., Allais-Bonnet A., Rocha D., Colle M.A., Klopp C., Esquerré D., Wurmser C., Flisikowski K., Schwarzenbacher H., Burgstaller J., Brügmann M., Dietschi E., Huth N., Freick M., Barbey S., Fayolle G., Danchin-Burge C., Schibler L., Bed’hom B., Hayes B.J., Daetwyler H.D., Fries R., Boichard D., Pin D., Drögemüller C., Capitan A. 2016. Rapid Discovery of De Novo Deleterious Mutations in Cattle Using Genome Sequence Data: Enhancing the Value of Farm Animals as Model Species. Scientific Reports, 7: 11466.
Michot P., Fritz S., Barbat A., Boussaha M., Deloche M.C., Grohs C., Hoze C., Le Berre L., Le Bourhis D., Desnoes O., Salvetti P., Schibler L., Boichard D., Capitan A. A missense mutation in PFAS is likely causal for embryonic lethality associated with the MH1 haplotype in Montbeliarde dairy cattle. J Dairy Sci, 100: 8176–8187.
Duchesne A., Vaiman A., Castille J., Beauvallet C., Gaignard P., Floriot S., Rodriguez S., Vilotte M., Boulanger L., Passet B., Albaric O., Guillaume F., Boukadiri A., Richard L., Bertaud M., Timsit E., Guatteo R., Jaffrézic F., Calvel P., Mahla R., Esquerré D., Péchoux C., Liu S., Vallat J.M., Boichard D., Slama A., Vilotte J.L. 2017. Bovine and murine models highlight novel roles for SLC25A46 in mitochondrial dynamics and metabolism, with implications for human and animal health. Plos Genet, 13: e1006597.
Fang Z.H., Bovenhuis H., Delacroix-Buchet A., Miranda G., Boichard D., Visker M.H.P.W., Martin P. 2017. Genetic and non-genetic factors contributing to differences in alpha-s-casein phosphorylation isoforms and other major milk proteins. J Dairy Sci, 100: 5564-5577.
Letaief R, Rebours E, Grohs C, Meersseman C, Fritz S, Trouilh L, Esquerré D, Barbieri J, Klopp C, Philippe R, Blanquet V, Boichard D, Rocha D, Boussaha M. 2017. Identification of copy number variation in French dairy and beef breeds using next-generation sequencing. Genet Sel Evol, 49: 77.
Sanchez M.P., Govignon-Gion A., Ferrand M., Gele M., Pourchet D., Miranda G., Martin P., Brochard M., Boichard D. 2017. Short-communication: Genetic parameters for milk protein composition in the French Montbéliarde, Normande and Holstein dairy cattle breeds. Journal of Dairy Science, 100: 6371-6375.
Boichard D, Ducrocq V, Croiseau P, Fritz S. 2016. Genomic selection in domestic animals: Principles, applications and perspectives. CR Biol, 339: 274-277.
Boichard D. , Grohs C. , Danchin C., Capitan A. 2016. Anomalies génétiques : définition, principes et concepts. INRA Productions Animales, 29: 297-306.
Grohs C, Duchesne A, Floriot S, Deloche MC, Boichard D, Ducos A, Danchin-Burge C. 2016. L’Observatoire National des Anomalies Bovines, son action et ses résultats pour une aide efficace à la gestion des anomalies génétiques. Inra Prod Anim, 29: 307-318.
Duchesne A, Grohs C, Michot P, Bertaud M, Boichard D, Floriot S, Capitan A. 2016. Du phénotype à la mutation causale : le cas des anomalies récessives bovines. Inra Prod Anim, 29: 319-328.
Fritz S., Michot P, Hoze C., Grohs C, Barbat A., Boussaha M., Boichard D, Capitan A. 2016. Anticiper l'émergence d'anomalies génétiques grâce aux données génomiques. INRA Productions Animales, 29: 339-350.
Boichard D, Grohs C, Michot P, Danchin C, Capitan A, Genestout L, Barbier S., Fritz S. 2016. Prise en compte des anomalies génétiques en sélection. INRA Productions Animales, 29: 351-358.
Boussaha M., Michot P., Letaief R., Hoze C., Fritz S., Grohs C., Esquerre D., Duchesne A., Philippe R., Blanquet V., Phocas F., Floriot S., Rocha D., Klopp C., Capitan A., Boichard D. 2016. Construction of a large collection of small genome variations in French dairy and beef breeds using whole genome sequences. Genetics Selection Evolution, 48: 87.
Kadri N.K., Harland C., Faux P., Cambisano N., Karim L., Coppieters W., Fritz S., Mullaart E., Baurain D., Boichard D., Spelman R., Charlier C., Georges M., Druet T. 2016. Sequence-based association analysis identifies coding and non coding variants in HFM1, MLH3, MSH4, MSH5, RNF212 and RNF212B with large effects on male and female recombination rate in cattle. Genome Research, 26: 1323-1332.
Van Den Berg I., Boichard D., Lund M.S. 2016. Sequence variants selected from a multi breed GWAS can improve the reliability of genomic prediction in dairy cattle. Genetics Selection Evolution, 48: 83.
Van Den Berg I., Boichard D., Lund M.S. 2016. Comparing power and precision of within and multi breed genome wide association studies of production traits using whole genome sequence data for five French and Danish dairy cattle breeds. Journal of Dairy Science, 99: 8932–8945.
Van Den Berg I., Boichard D., Guldbrandtsen B., Lund M.S. 2016. Use of sequence variants to improve accuracy of genomic prediction in dairy cattle breeds. G3, 6: 2553-2561.
Michot P., Chahory S., Marete A., Grohs C., Dagios D., Donzel E., Aboukadiri A., Deloche M.C., Allais-Bonnet A., Chambrial M., Barbey S., Boussaha M., Danchin-Burge C., Fritz S., Boichard D., Capitan A. 2016. A reverse genetic approach identifies an ancient frameshift mutation in RP1 causing recessive progressive retinal degeneration in European cattle breeds. Genetics Selection Evolution, 48: 56.
Sanchez M.P. , Govignon-Gion A., Ferrand M., Gele M., Pourchet D., Amigues Y., Fritz S., Boussaha M., Capitan A., Rocha D., Miranda G., Martin P., Brochard M., Boichard D. 2016. Whole genome scan to detect SNP associated to milk protein composition in three French dairy cattle breeds. Journal of Dairy Science, 99: 8203–8215
Colleau J. J., Fritz S., Guillaume F., Baur A., Dupassieux D., Boscher M.Y., Journaux L., Eggen A., Boichard D. 2015. Simulation des potentialités de la sélection génomique chez les bovins laitiers. INRA Productions Animales, 28: 251-258.
Boussaha M., Esquerre D., Barbieri J., Djari A., Pinton A., Letaief R., Salin G., Escudie F., Roulet A., Fritz S., Samson F., Grohs C., Bernard M., Klopp C., Boichard D., Rocha D. 2015. Genome-wide study of structural variants in bovine Holstein, Montbeliarde and Normande dairy breeds. Plos One, 10: e0135931.
Dezetter C., Leclerc H., Mattalia S., Barbat A., Boichard D., Ducrocq V. 2015. Inbreeding and Crossbreeding Parameters for Production and Fertility Traits in Holstein, Montbéliarde, and Normande Cows. Journal of Dairy Science, 98: 4904–4913.
Brøndum R.F, Su G., Janss L., Sahana G., Guldbrandtsen B., Boichard D., Lund M.S. 2015. QTL markers derived from whole genome sequence data increases the reliability of genomic prediction. J Dairy Sci, 98: 4107-4116.
Floriot S., Vesque C., Rodriguez S., Bourgain-Guglielmetti F., Karaiskou A., Gautier M., Duchesne A., Barbey S., Fritz S., Vasilescu A., Bertaud M., Moudjou M., Halliez S., Cormier-Daire V., El Hokayem J., Nigg E.A., Manciaux L., Guatteo R., Cesbron N., Toutirais G., Eggen A., Schneider-Maunoury S., Boichard D., Sobczak-Thépot J., Schibler L. 2015. C-Nap1 mutation affects centriole cohesion and is associated with a Seckel-like syndrome in cattle. Nature Communications, 6: 6894.
Michot P., Fantini O., Braques R., Allais-Bonnet A., Saintilan R., Grohs C., Barbieri J., Genestout L., Danchin C., Gourreau J.M., Boichard D., Pin D., Capitan A. 2015. Whole-genome sequencing identifies a homozygous deletion encompassing exons 17 to 22 of the Integrin Beta 4 Gene in a Charolais calf with Junctional Epidermolysis Bullosa. Genetics Selection Evolution, 47: 37.
Baumung R., Farkas J., Boichard D., Meszaros G., Sölkner J., Curik I. 2015. GRAIN: a computer program to calculate ancestral and partial inbreeding coefficients using a gene dropping approach. Journal of Animal Breeding and Genetics, 132: 100-108.
Boichard D., Ducrocq V., Fritz S. 2015. Sustainable dairy cattle selection in the genomic era. Journal of Animal Breeding and Genetics, 132: 135-143.
Capitan A., Michot P., Baur A., Saintilan R., Hoze C., Valour D., Guillaume F., Boichon D., Barbat A., Boichard D., Schibler L., Fritz S. 2015. Genetic tools to improve reproduction traits in dairy cattle. Reprod. Fert. Dev, 27: 14-21
Boichard D. 2014. Quel futur pour l’amélioration génétique chez les espèces domestiques ? Bulletin de l’Académie Vétérinaire de France, 167: 103-108.
Boichard D., Govignon-Gion A., Larroque H., Maroteau C., Palhiere I., Tosser-Klopp G., Rupp R., Sanchez M.P., Brochard M. 2014. Déterminisme génétique de la composition en acides gras et protéines du lait des ruminants. INRA Productions Animales, 27: 283-298.
Daetwyler H.D., Capitan A., Pausch H., Stothard P., Van Binsbergen R., Brøndum R.F., Liao X., Djari A., Rodriguez S.C., Grohs C., Esquerré D., Bouchez O., Rossignol M.N., Klopp C., Rocha D., Fritz S., Eggen A., Bowman P., Coote D., Chamberlain A.J., Anderson C., Van Tassell C.P., Hulsegge I., Goddard M.E., Guldbrandtsen B., Lund M.S., Veerkamp R.F., Boichard D., Fries R., Hayes B.J. 2014. Whole-genome sequencing of 234 bulls facilitates mapping of monogenic and complex traits in cattle. Nature Genetics, 46: 858-867.
Hozé C., Fritz S., Phocas F., Boichard D., Ducrocq V., Croiseau P. 2014. Efficiency of multi-breed genomic selection for dairy cattle breeds with different sizes of reference population. Journal of Dairy Science, 97: 3918-3929.
Labatut J., Astruc J.M., Barillet F., Boichard D., Ducrocq V., Griffon L., Lagriffoul G. 2014. Implications organisationnelles de la sélection génomique: analyses et accompagnement. INRA Productions Animales, 27: 303-316.
Rocha D., Billerey C., Boichard D., Boussaha M. 2014. Identification of the putative ancestral allele of bovine single nucleotide polymorphisms. Journal of Animal Breeding and Genetics, 131: 483-486.
Van Den Berg I., Fritz I., Rodriguez S., Rocha D., Boussaha M., Lund M.S., Boichard D. 2014. Concordance analysis for QTL detection in dairy cattle: a case study of leg morphology. Genetics Selection Evolution, 46: 31.
Allais-Bonnet A., Grohs C., Medugorac I., Krebs S., Djari A., Graf A., Fritz S., Seichter D., Baur A., Bouet S., Wahlberg P., Esquerre D., Hoze C., Boussaha M., Weiss B., Thepot D., Venot E., Fouilloux M.N., Rossignol M.N., Van Marle-Köster E., Hreiðarsdottir G.E., Barbey S., Dozias D., Cobo E., Reverse P., Catros O., Marchand J.L., Soulas P., Roy P., Marquant-Leguienne B., Lebourhis D., Pannetier M., Phocas F., Klopp C., Rocha D., Fouchet M., Journaux L., Bernard-Capel C., Eggen A., Förster M., Gallard Y., Boichard D., Pailhoux E., Capitan A. 2013. Novel insights into the bovine polled phenotype and horn ontogenesis in Bovidae. Plos One, 8: e63512.
Boichard D., 2013. La sélection génomique : une opportunité pour l’amélioration de la santé des animaux d’élevage. Bulletin de l’Académie Vétérinaire de France, 166: 25-31.
Brochard M., Boichard D., Ducrocq V., Fritz S. 2013. La sélection pour des vaches et une production laitière plus durables : acquis de la génétique et opportunités offertes par la sélection génomique. INRA Prod Anim, 26: 139-150.
Fritz S., Capitan A., Djari A., Rodriguez S.C., Barbat A., Baur A., Grohs C., Weiss B., Boussaha M., Esquerre D., Klopp C., Rocha D., Boichard D. 2013. Detection of haplotypes associated with prenatal death in dairy cattle and identification of deleterious mutations in GART, SHBG, and SLC37A2. Plos One, 8: e65550.
Hoze C., Fouilloux M.N., Venot E., Guillaume F., Dassonneville R., Fritz S., Ducrocq V., Phocas F., Boichard D., Croiseau P. 2013. High density marker imputation efficiency in 16 French cattle breeds. Genet Sel Evol, 45: 33.
Van Den Berg I., Fritz S., Boichard D. 2013. QTL fine mapping with Bayesian C(π): a simulation study. Genet Sel Evol, 45: 19.
Boichard D., Brochard M. 2012. New phenotypes for new breeding goals in dairy cattle. Animal, 6: 544-550.
Boichard D., Guillaume F., Baur A., Croiseau P., Rossignol M.N., Boscher M.Y., Druet T., Genestout L., Colleau J.J., Journaux L., Ducrocq V., Fritz S. 2012. Genomic Selection in French Dairy Cattle. Animal Production Science, 52: 115-120.
Boichard D., Chung H., Dassonneville R., David X., Eggen A., Fritz S., Gietzen K.J., Hayes B.J., Lawley C.T., Sonstegard T.S., Van Tassell C.P., Vanraden P.M., Viaud K., Wiggans G.R. 2012. Design of a Bovine Low-Density SNP Array Optimized for Imputation. PLoS ONE, 7: e34130.
Capitan A., Bonnet A., Pinton A., Marquant-Le Guienne B., Le Bourhis D., Grohs C., Bouet S., Clement L., Salas-Cortes L., Venot E., Chaffaux S., Weiss B., Delpeuch A., Noe G., Rossignol M.N., Barbey S., Dozias D., Cobo E., Barasc H., Auguste A., Pannetier M., Deloche M.C., Lhuilier E., Bouchez O., Esquerre D., Salin G., Klopp C., Donnadieu C., Chantry-Darmon C., Hayes H., Gallard Y, Ponsart C., Boichard D., Pailhoux E. 2012. A 3.7 Mb deletion encompassing ZEB2 causes a novel Polled and Multisystemic Syndrome in the progeny of a somatic mosaic bull. Plos One, 7: e49084.
Dassonneville R., Baur A., Fritz S., Boichard D., Ducrocq V. 2012. Inclusion of cows records in genomic evaluations and its impact on bias due to preferential treatment. Genet Sel Evol, 44: 40.
Dassonneville R., Fritz S., Ducrocq V., Boichard D. 2012. Imputation performances of three low density marker panels in beef and dairy cattle. Journal of Dairy Science, 95: 4136–4140.
Dayo G.K., Gautier M., Berthier D., Poivey J.P., Sidibe I., Bengaly Z., Eggen A., Boichard D., Thevenon S. 2012. Association studies in QTL regions linked to bovine trypanotolerance in a West African Crossbred Population. Animal Genetics, 43: 123-132.
Hou Y., Bickhart D.M., Hvinden M.L., Li C., Song J., Boichard D., Fritz S., Eggen A., Denise S., Wiggans G.R., Sonstegard T.S., Van Tassell C.P., Liu G.E. 2012. Fine mapping of copy number variations on two cattle genome assemblies using high density SNP array. BMC Genomics, 13: 376.
Ytournel F., Teyssedre S., Roldan D., Erbe M., Simianer H., Boichard D., Gilbert H., Druet T., Legarra A. 2012. LDSO: A program to simulate pedigrees and molecular information under various evolutionary forces. Journal of Animal Breeding and Genetics, 5: 417-421.
Croiseau P., Legarra A., Guillaume F., Fritz S., Baur A., Boichard D., Ducrocq V. 2011. Fine tuning genomic evaluations in dairy cattle through SNP pre-selection with the Elastic-Net algorithm. Genetics Research, 93: 409-417.
Guillaume F., Boichard D., Ducrocq V., Fritz S. 2011. Utilisation de la sélection génomique chez les bovins laitiers. INRA Prod Anim, 24: 363-368.
Barbat A., Le Mezec P., Ducrocq V., Mattalia S., Fritz S., Boichard D., Ponsart C., Humblot P. 2010. Female Fertility in French Dairy Breeds: Current Situation and Strategies for Improvement. Journal of Reproduction and Development, 56: S15-S21.
Bidanel J.P., Boichard D., Chevalet C. 2008. De la génétique à la génomique. INRA Productions Animales, 21: 15-32.
Druet T., Fritz S., Boussaha M., Ben Jemaa S., Derbala D., Zele D., Lechner D., Charon C., Boichard D., Gut I.G., Eggen A., Gautier M. 2008. Fine-mapping of QTLs affecting female fertility in dairy cattle on BTA03 using a dense SNP map. Genetics, 178: 2227-2235.
Guillaume F., Fritz S., Boichard D., Druet T. 2008. Estimation by simulation of the efficiency of the French marker-Assisted selection program in dairy cattle. Genetics Selection Evolution, 40: 91-102.
Gautier M, Fritz S., Capitan A., Eggen A., Boichard D., Druet T. 2007. Characterization of the K232A and VNTR polymorphisms in the DGAT1 gene in French dairy cattle. J. Dairy Sci, 90: 2980-2988.
Gautier M., Faraut T., Moazami-Goudarzi K., Navratil V., Foglio M., Grohs C., Boland A., Garnier J.G., Boichard D., Lathrop G.M., Gut I.G., Eggen A. 2007. Genetic and haplotypic structure in 14 European and African cattle breeds. Genetics: 177, 1059-1070.
Druet T., Fritz S., Boichard D., Colleau J.J. 2006. Estimation of genetic parameters for quantitative trait loci for dairy traits in the French Holstein population. Journal of Dairy Science, 89: 4070-4076.
Barnouin J., Chassagne M., Bazin S., Boichard D., 2004. Management and hygiene practices form questionnaire surveys in herds with very low somatic cell score through the ‘Objective Zero Mastitis’ national programme in France J Dairy Sci, 87: 3989-3999.
Bennewitz J, Reinsch N., Guiard V., Fritz S., Thomsen H., Looft C., Kühn C., Schwerin M., Weimann C., Erhardt G., Reinhardt F., Reents R., Boichard D., Kalm E. 2004. Multiple Quantitative Trait Loci Mapping With Cofactors and Application of Alternative Variants of the False Discovery Rate in an Enlarged Granddaughter Design. Genetics, 168: 1019–1027.
Schibler L., Roig A., Mahe M.F., Save J.C., Gautier M., Taourit S., Boichard D., Eggen A., Cribiu E.P.. 2004. A first generation bovine BAC-based physical map. Genet Sel Evol, 36: 105-122.
Boichard D., Grohs C., Bourgeois F., Cerqueira F., Faugeras R., Neau A., Rupp R., Amigues Y., Boscher M.Y., Leveziel H., 2003. Detection of genes influencing economic traits in three French dairy cattle breeds. Genet Sel Evol, 35: 77-101.
Druet T., Jaffrezic F., Boichard D., Ducrocq V., 2003. Estimation of genetic parameters for first parity lactation curves of French Holstein cows. J. Dairy Sci, 86: 2480-2490.
Rupp R., Boichard D., 2003. Genetics of resistance to mastitis in dairy cattle. Vet Res, 34: 671-688.
Rupp R., Boichard D. 2000. Relationship of early first lactation somatic cell count with risk of subsequent first clinical mastitis. Livest Prod Sci, 62: 169-180
Rupp R., Beaudeau F. Boichard D., 2000. Relationship between milk somatic cell counts in the first lactation and clinical mastitis in the second lactation of French Holstein cows. Prev Vet Med, 46: 99-111.
Rupp R., Boichard D. 1999. Genetic parameters for clinical mastitis, somatic cell score, production, udder type traits, and milking ease in first lactation Holsteins. J. Dairy Sci, 82: 2198-2204.
Robert-Granie C., Bonaiti B., Boichard D., Barbat A. 1999. Accounting for variance heterogeneity in French dairy cattle genetic evaluation. Livest Prod Sci, 60: 343-357.
Zhang Q., Boichard D., Bishop M., Hoeschele I., Ernst C., Doud L., Eggen A., Jurgella G., Murkve B., Pfister-Genskow M., Thorbahn D., Grignola Fe, Uimari P., Thaller G. 1998. Mapping quantitative trait loci for milk production and health of dairy cattle in a large outbred pedigree. Genetics, 149: 1959-1973.
Boichard D., Maignel L., Verrier E. 1997. The value of using probabilities of gene origin to measure genetic variability in a population. Genet Sel Evol, 29: 5-23.
Boichard D., Bonaiti B., Barbat A., Mattalia S. 1995. Three methods to validate the estimation of genetic trend for dairy cattle. J Dairy Sci, 78: 431-437.
Boichard D., Manfredi E. 1994. Genetic analysis of conception rate in French Holstein dairy cattle. Acta Agric Scand Sect A, 44: 138-145.
Foulley J.L., Hanocq E., Boichard D. 1992. A criterion for measuring the degree of connectedness in linear models of genetic evaluation. Genet Sel Evol, 24: 315-330.
Boichard D. 1990. Estimation of the economic value of conception rate in dairy cattle. Livest Prod Sci, 24: 187-204.
Boichard D, Bonaiti B. 1987. Genetic parameters for first lactation dairy traits in Friesian, Montbéliarde and Normande breeds. Genet Sel Evol, 19: 337-350.
